Amantadine may reverse punding in Parkinson's disease—Observation in a patient
Identifieur interne : 002A09 ( Main/Exploration ); précédent : 002A08; suivant : 002A10Amantadine may reverse punding in Parkinson's disease—Observation in a patient
Auteurs : Kenichi Kashihara [Japon] ; Takaki Imamura [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-01.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Amantadine, Amantadine (therapeutic use), Behavioral disorder, Dopamine Agents (therapeutic use), Drug Administration Schedule, Female, Human, Humans, Nervous system diseases, Parkinson Disease (complications), Parkinson disease, Parkinson's disease, Stereotypic Movement Disorder (complications), Stereotypic Movement Disorder (drug therapy), Stereotypy, Treatment, amantadine, punding, stereotypy, treatment.
- MESH :
- chemical , therapeutic use : Amantadine, Dopamine Agents.
- complications : Parkinson Disease, Stereotypic Movement Disorder.
- drug therapy : Stereotypic Movement Disorder.
- Aged, Drug Administration Schedule, Female, Humans.
Abstract
Punding, complex stereotyped behavior, sometimes occurs in patients with Parkinson's disease under dopaminergic replacement therapy. Reduction of dopaminergic drugs may reduce the problem but risks enhancing motor impairment. We report a patient with Parkinson's disease presenting disabling punding, which was reversed by amantadine without aggravating motor function. Amantadine may reduce punding by blocking NMDA receptors, in the same manner as in levodopa‐induced dyskinesias. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21780
Affiliations:
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Le document en format XML
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Reduction of dopaminergic drugs may reduce the problem but risks enhancing motor impairment. We report a patient with Parkinson's disease presenting disabling punding, which was reversed by amantadine without aggravating motor function. Amantadine may reduce punding by blocking NMDA receptors, in the same manner as in levodopa‐induced dyskinesias. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Kashihara, Kenichi" sort="Kashihara, Kenichi" uniqKey="Kashihara K" first="Kenichi" last="Kashihara">Kenichi Kashihara</name></noRegion><name sortKey="Imamura, Takaki" sort="Imamura, Takaki" uniqKey="Imamura T" first="Takaki" last="Imamura">Takaki Imamura</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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